04.03 Alprazolam (Xanax)

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Generic Name


Trade Name



Anxiety, panic disorder, manage symptoms of PMS, insomnia, mania, psychosis


Works in CNS to produce anxiolytic effect causing CNS depression.

Therapeutic Class

Antianxiety agent

Pharmacologic Class


Nursing Considerations

• Use caution with existing CNS depression, sleep apnea, renal dysfunction,
hepatic dysfunction.
• May cause CNS depression, drowsiness, lethargy
• May lead to physical dependence, may experience tolerance effect
• Assess anxiety and mental status
• Romazicon (flumazenil) is the antidote for overdose
• Grapefruit juice may increase blood levels

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Module 0 – Pharmacology Course Introduction

Module 3 – Disease Specific Medications

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