08.07 Fluoxetine (Prozac)

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Generic Name


Trade Name



Depressive disorder, OCD, bulimia, panic disorder, bipolar, anorexia, ADHD, DM
neuropathy, obesity


Inhibits reuptake of serotonin allowing it to persist longer in the synaptic cleft

Therapeutic Class


Pharmacologic Class


Nursing Considerations

• Do not use while taking MAOIs
• May cause suicidal thoughts, drowsiness, anxiety, sexual dysfunction,
insomnia, palpitations
• Monitor closely for serotonin syndrome
• Concurrent use with certain medications may lead to QT prolongation
• Monitor mood changes and assess for suicidal ideation
• Monitor nutrition status
• May cause elevated liver enzymes
• Instruct pt to maintain good oral hygiene

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Module 0 – Pharmacology Course Introduction

Module 3 – Disease Specific Medications

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