12.13 Azithromycin (Zithromax)

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Generic Name

Azithromycin

Trade Name

Zithromax

Indication

URI, chronic bronchitis, lower respiratory infections, otitis media, skin infections, various STIs, prevention of bacterial endocarditis, treatment of cystic fibrosis

Action

Inhibits bacterial protein synthesis

Therapeutic Class

Agents for atypical mycobacterium, anti-infectives

Pharmacologic Class

Macrolide

Nursing Considerations

• May lead to pseudomembranous colitis, pain, diarrhea, nausea,
Stevens-Johnson syndrome, angioedema
• May increase risks for warfarin toxicity
• Monitor patient for signs of anaphylaxis
• Instruct patient to notify physician for diarrhea, or blood or pus in stool
• Instruct patient to take medication exactly as prescribed

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