22.05 Celecoxib (Celebrex)

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Generic Name


Trade Name



Osteoarthritis, rheumatoid arthritis, acute pain


Decreases pain and inflammation by inhibiting synthesis of prostaglandins

Therapeutic Class


Pharmacologic Class

Cox 2 inhibitor

Nursing Considerations

• Use caution with cardiovascular disease
• Increases risk for MI, CVA, thrombosis
• May cause GI bleeding, Stevens-Johnson syndrome, dermatitis
• Notify provider for new-onset abdominal pain or black stool

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