24.04 Fentanyl (Duragesic)

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Generic Name

Fentanyl

Trade Name

Sublimaze

Indication

Supplement to general anesthesia, continuous IV infusion for purpose of analgesia

Action

Binds to opiate receptors in CNS altering perception of pain, producing CNS
depression

Therapeutic Class

Opioid Analgesic

Pharmacologic Class

Opioid agonists

Nursing Considerations

• Use caution with increased ICP, head trauma, adrenal insufficiency
• Avoid use with MAOIs
• May cause apnea, laryngospasm, decreased respirations, bradycardia,
hypotension
• Do not consume grapefruit while taking this medication
• Monitor hemodynamics during administration
• Assess patient pain scale frequently

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