04.04 Lorazepam (Ativan)

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Generic Name


Trade Name



anxiety, sedation, seizures


general CNS depression by potentiating inhibitory neurotransmitters

Therapeutic Class

anesthetic adjuncts, antianxiety agents, sedative hypnotics

Pharmacologic Class


Nursing Considerations

• use caution with COPD and sleep apnea
• avoid alcohol use
• antidote is Flumazenil (Romazicon)
• may cause apnea, cardiac arrest, bradycardia, hypotension
• use caution with other CNS depressants
• administer slowly and dilute to decrease complications

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Module 0 – Pharmacology Course Introduction

Module 3 – Disease Specific Medications

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