26.06 Methylprednisolone (Solu-Medrol)

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Generic Name


Trade/Brand Name



  • Inflammation, allergy, autoimmune disorders
  • Prevent organ rejection


  • Suppress inflammation and normal immune response
  • The adrenal glands excrete steroid hormones that play a role
    • Increasing blood sugars
    • immune suppression
    • metabolism of fat, protein, and carbohydrates
    • As well as decreasing bone formation

Therapeutic Class

  • Antiasthmatics
  • Corticosteroids

Pharmacologic Class


Nursing Considerations

  • Avoid in active untreated infections
  • May cause
    • CNS alterations
    • Peptic ulcers
    • Cushingoid appearance (buffalo hump, moon face)
    • Increased cholesterol and lipid values
  • Decrease wound healing
  • Depresses immune system
    • Report signs of infection (sore throat)

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Module 0 – Pharmacology Course Introduction

Module 3 – Disease Specific Medications

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