24.10 Nalbuphine (Nubain)

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Generic Name


Trade Name



pain, analgesia during labor, sedation before surgery, supplement to balance anesthesia


alters perception and response to pain, causes CNS depression

Therapeutic Class

Opioid Analgesic

Pharmacologic Class

opioid agonists/analgesics

Nursing Considerations

• use caution with head trauma
• can cause dizziness, headache, nausea, vomiting, respiratory depression
• do not use with MAOIs
• assess pain
• may cause respiratory in newborn
• asses hemodynamic parameters
• may elevate pancreatic enzymes
• Narcan (naloxone) is the antidote

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