27.04 Nitroglycerin (Nitrostat)

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Generic Name

Nitroglycerin

Trade/Brand Name

Nitrostat

Indication

  • Prevention of angina
  • Heart failure
  • Anal fissures
  • Severe hypertension
  • Acute MI

Action

  • Enters vascular smooth muscle
    • Nitric oxide causes relaxation of smooth muscle cells
      • Vasodilation occurs

Therapeutic Class

  • Antianginal agent
  • Vasodilator

Pharmacologic Class

Vasodilator

Nursing Considerations

  • May cause
    • Blurred vision
    • Dryness of the mouth
    • Skin reactions
  • Contraindications
    • Severe anemia
    • Increased ICP
  • Monitor
    • Hemodynamics
    • Chest pain

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