17.10 Omeprazole (Prilosec)

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Generic Name


Trade Name



GERD, ulcers, Zollinger-Ellison syndrome, reduce the risk of GI bleed in critically ill patients, heart burn


prevents the transport of H ions into the gastric lumen by binding to gastric parietal cells, ↓ gastric acid production

Therapeutic Class

antiulcer agent

Pharmacologic Class

proton-pump inhibitor

Nursing Considerations

• take 30-60 minutes prior to eating
• capsules should be swallowed whole
• instruct patient to report black tarry stool

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