17.11 Pantoprazole (Protonix)

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Generic Name


Trade Name



GERD, heartburn, reduce the risk of GI bleed in critically ill patients


prevents the transport of H ions into the gastric lumen by binding to gastric parietal cells, ↓ gastric acid production

Therapeutic Class

antiulcer agents

Pharmacologic Class

proton-pump inhibitors

Nursing Considerations

• can cause hyperglycemia, abdominal pain
• decreases absorption of certain drugs
• may increase bleeding with warfarin
• assess for occult blood
• assess liver enzymes
• assess symptoms of heart burn
• administer slowly via IV push

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