08.08 Paroxetine (Paxil)

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Generic Name


Trade Name



major depressive disorder, OCD, anxiety, PTSD


block reuptake of serotonin in CNS

Therapeutic Class

antianxiety agent, antidepressant

Pharmacologic Class


Nursing Considerations

• do not use with MAOIs
• can cause neurolyptic malignant syndrome, suicidal thoughts, serotonin syndrome, constipation,
diarrhea, insomnia
• decrease effectiveness of digoxin
• increase bleeding with warfarin
• assess for suicidal thoughts

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Module 0 – Pharmacology Course Introduction

Module 3 – Disease Specific Medications

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