10.07 Ranitidine (Zantac)

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Generic Name

ranitidine

Trade Name

Zantac

Indication

duodenal ulcers, GERD, heartburn, esophagitis, GI bleed

Action

inhibits action of histamine in gastric parietal cells, decreases gastric acid secretion

Therapeutic Class

antiulcer agents

Pharmacologic Class

histamine H2 antagonists

Nursing Considerations

• may cause arrhythmias, agranulocytosis, aplastic anemia, confusion
• assess abdominal pain
• monitor for blood in stool
• monitor CBC

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