12.05 Rifampin (Rifadin)

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Generic Name

rifampin

Trade Name

Rimactane

Indication

tuberculosis

Action

inhibits RNA synthesis

Therapeutic Class

Antitubercular

Pharmacologic Class

rifamycins

Nursing Considerations

• can turn body fluids red
• may cause diarrhea, nausea, vomiting, confusion
• assess lung sounds and sputum characteristics
• evaluate renal and liver function tests
• instruct patient not to skip or double dose
• must complete entire dose (6-12 month therapy)

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