28.04 Vasopressin (Pitressin)

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Generic Name


Trade Name



management of diabetes insipidus, VT/VF unresponsive to initial shock, GI hemorrhage


increases water permeability of the kidney’s collecting duct and distal convoluted tubule leading to water retention, also increases peripheral vascular resistance leading to increased BP

Therapeutic Class


Pharmacologic Class

antidiuretic hormone

Nursing Considerations

• use caution with HF and CV disease
• contraindicated in renal failure and hypersensitivity to pork
• monitor BP, HR, and EKG during therapy
• monitor urine specific gravity and osmolality
• weigh patient and assess for edema
• monitor electrolyte panel
• do not use with alcohol

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